Sensitive

Breast cancer subtype (triple negative vs luminal A-like)

C11orf65 · rs10890841

Where this position leads

Condition: Breast Cancer

rs10890841 Condition: Breast Cancer Breast Cancer Condition rs10890841 rs10890841 C11orf65

What the study found

Who was studied 16,499 European ancestry triple negative cases, 60,715 European ancestry luminal A-like cases.

The effect Each copy of the T allele shifted the measure 0.021 higher (95% confidence interval 0.013-0.029); p = 2 × 10−9.

Where it sits Chromosome 11, band 11q22.3 — in an intron of C11orf65.

What each result means

C/C No copy of the version the research linked to Breast cancer subtype (triple negative vs luminal A-like). This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to Breast cancer subtype (triple negative vs luminal A-like). That is a smaller link than two copies.
T/T Two copies of the version the research linked to Breast cancer subtype (triple negative vs luminal A-like). That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs10890841

What is rs10890841?

rs10890841 is a single position in the genome, in or near the C11orf65 gene. Published research associates it with breast cancer subtype (triple negative vs luminal a-like). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs10890841 linked to?

On MyGeneLog this position is linked to Breast Cancer. The research behind each link, and its sources, are set out on that condition page.

Does having rs10890841 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs10890841 come from?

GWAS Catalog, Cancer research 2024, PMID:38832928. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Breast cancer subtype (triple negative vs luminal A-like) (rs10890841). MyGeneLog™. https://www.mygenelog.com/variants/rs10890841

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