A/APublished research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Cholesterol, total compared to the general population.
A/GPublished research associates this genotype (one copy of the reported risk allele) with an intermediate association with Cholesterol, total.
G/GPublished research associates this genotype with typical/baseline likelihood of Cholesterol, total — no copies of the reported risk allele.
Genome medicine · 2017 · PMID 28270201 · open access
Questions about rs10889333
What is rs10889333?
rs10889333 is a single position in the genome, in or near the DOCK7 gene. Published research associates it with cholesterol, total. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs10889333 linked to?
On MyGeneLog this position is linked to Cholesterol (LDL, HDL and Total). The research behind each link, and its sources, are set out on that condition page.
Does having rs10889333 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs10889333 come from?
GWAS Catalog, Genome Med 2017, PMID:28270201. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.