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Hemoglobin levels

PRRC2A · rs10885

Where this position leads

Condition: Blood Cell Counts

rs10885 Condition: Blood Cell Counts Blood Cell Counts Condition rs10885 rs10885 PRRC2A

What the study found

Who was studied 684,122 European ancestry individuals.

The effect Each copy of the T allele shifted the measure 0.035 lower; p = 2 × 10−36.

Where it sits Chromosome 6, band 6p21.33 — a missense change in PRRC2A.

What ClinVar records

Classification Benign for PRRC2A-related disorder; no assertion criteria provided (0 of 4 stars, 1 submitter), last evaluated 2019-10-21. ClinVar record 3058971 NM_004638.4(PRRC2A):c.6016C>T (p.Pro2006Ser)

What this is ClinVar's aggregate record for this position (as of its 2026-10-12 release), not a result about you. A classification describes the variant against the condition named, as laboratories submitted it. Whether a person carries this variant, and what that would mean for them, is a question for a clinical test and a genetic counsellor.

What each result means

C/C No copy of the version the research linked to Hemoglobin levels. This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to Hemoglobin levels. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Hemoglobin levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs10885

What is rs10885?

rs10885 is a single position in the genome, in or near the PRRC2A gene. Published research associates it with hemoglobin levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs10885 linked to?

On MyGeneLog this position is linked to Blood Cell Counts. The research behind each link, and its sources, are set out on that condition page.

Does having rs10885 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs10885 come from?

GWAS Catalog, Communications biology 2020, PMID:32327693. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Hemoglobin levels (rs10885). MyGeneLog™. https://www.mygenelog.com/variants/rs10885

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