CALHM1 · rs10883870
Stands on its own. Nothing else here links to this position yet — but the page above is the point: what the research found, what each genotype means, and where it came from, in language you can read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 1,205,871 European ancestry individuals, 168,300 East Asian ancestry individuals, 63,553 African ancestry individuals, 23,509 Hispanic or Latin American individuals, 22,103 African American individuals, 21,791 Central Asian or South Asian ancestry individuals, 1,502 Middle Eastern ancestry individuals, 939 other admixed ancestry individuals, 602 Native American ancestry individuals, 150 Asian ancestry individuals, 339 individuals.
The effect Each copy of the G allele shifted the measure 6.7 z score higher; p = 2 × 10−11.
How common The G allele had a frequency of about 36% in the people studied.
Where it sits Chromosome 10, band 10q24.33 — in an intron of CALHM1.
rs10883870 is a single position in the genome, in or near the CALHM1 gene. Published research associates it with estimated glomerular filtration rate (creatinine). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
GWAS Catalog, Nature genetics 2022, PMID:35710981. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Estimated glomerular filtration rate (creatinine) (rs10883870). MyGeneLog™. https://www.mygenelog.com/variants/rs10883870