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Sex hormone-binding globulin levels

RXRA · rs10881582

What the study found

Who was studied 148,248 British ancestry men.

The effect Each copy of the A allele shifted the measure 0.55 nmol/L higher (95% confidence interval 0.37-0.73); p = 2 × 10−9.

How common The A allele had a frequency of about 24% in the people studied.

Where it sits Chromosome 9, band 9q34.2 — in an intron of RXRA.

What each result means

A/A Two copies of the version the research linked to Sex hormone-binding globulin levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to Sex hormone-binding globulin levels. That is a smaller link than two copies.
G/G No copy of the version the research linked to Sex hormone-binding globulin levels. This is the starting point the study compared everyone against.
Source

Questions about rs10881582

What is rs10881582?

rs10881582 is a single position in the genome, in or near the RXRA gene. Published research associates it with sex hormone-binding globulin levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs10881582 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs10881582 come from?

GWAS Catalog, Science advances 2021, PMID:34321204. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Sex hormone-binding globulin levels (rs10881582). MyGeneLog™. https://www.mygenelog.com/variants/rs10881582

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