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Birth weight (winsorised)

near RNA5SP362 · rs10878369

Where this position leads

Condition: Birth Weight

rs10878369 Condition: Birth Weight Birth Weight Condition rs10878369 rs10878369 near RNA5SP3…

What the study found

Who was studied 241,168 British ancestry individuals.

The effect Each copy of the C allele shifted the measure 0.0123 kg higher (95% confidence interval 0.0089-0.0157); p = 1 × 10−12.

Where it sits Chromosome 12, band 12q14.3 — between genes, 13.1 kb from RNA5SP362.

What each result means

C/C Two copies of the version the research linked to Birth weight (winsorised). That is the strongest link of the three results. A link in a study is not a diagnosis.
C/G One copy of the version the research linked to Birth weight (winsorised). That is a smaller link than two copies.
G/G No copy of the version the research linked to Birth weight (winsorised). This is the starting point the study compared everyone against.
Source

Questions about rs10878369

What is rs10878369?

rs10878369 is a single position in the genome, in or near the near RNA5SP362 gene. Published research associates it with birth weight (winsorised). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs10878369 linked to?

On MyGeneLog this position is linked to Birth Weight. The research behind each link, and its sources, are set out on that condition page.

Does having rs10878369 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs10878369 come from?

GWAS Catalog, Diabetologia 2025, PMID:40210729. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Birth weight (winsorised) (rs10878369). MyGeneLog™. https://www.mygenelog.com/variants/rs10878369

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