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Snoring

MSRB3 · rs10878269

What the study found

Who was studied 151,836 British ancestry cases, 255,230 British ancestry controls.

The effect Each copy of the C allele shifted the measure 0.00921 lower (95% confidence interval 0.0071-0.0113); p = 5 × 10−18.

Where it sits Chromosome 12, band 12q14.3 — in an intron of MSRB3.

What each result means

C/C Two copies of the version the research linked to Snoring. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/T One copy of the version the research linked to Snoring. That is a smaller link than two copies.
T/T No copy of the version the research linked to Snoring. This is the starting point the study compared everyone against.
Source

Questions about rs10878269

What is rs10878269?

rs10878269 is a single position in the genome, in or near the MSRB3 gene. Published research associates it with snoring. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs10878269 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs10878269 come from?

GWAS Catalog, Nature communications 2020, PMID:32060260. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Snoring (rs10878269). MyGeneLog™. https://www.mygenelog.com/variants/rs10878269

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