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Energy intake

ANKRD33 · rs10876214

What the study found

Who was studied 5,461 European ancestry lean females, 2,726 European ancestry lean males, 6,563 European ancestry overweight or obese females, 4,020 European ancestry overweight or obese males..

The effect Each copy of the T allele shifted the measure 58 kcals higher (95% confidence interval 39-77); p = 1 × 10−9.

How common The T allele had a frequency of about 32% in the people studied.

Where it sits Chromosome 12, band 12q13.13 — between genes, 10.7 kb from FIGNL2-DT.

What each result means

C/C No copy of the version the research linked to Energy intake. This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to Energy intake. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Energy intake. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs10876214

What is rs10876214?

rs10876214 is a single position in the genome, in or near the ANKRD33 gene. Published research associates it with energy intake. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs10876214 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs10876214 come from?

GWAS Catalog, PLoS One 2018, PMID:30071075. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Energy intake (rs10876214). MyGeneLog™. https://www.mygenelog.com/variants/rs10876214

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