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Glomerular filtration rate (creatinine)

LPHN2 · rs10874312

Stands on its own. Nothing else here links to this position yet — but the page above is the point: what the research found, what each genotype means, and where it came from, in language you can read. Links to conditions, drugs and the senses appear automatically if we write them.

What each result means

A/A Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Glomerular filtration rate (creatinine) compared to the general population. (GWAS Catalog, Sci Rep 2017, PMID:28452372)

A/G Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Glomerular filtration rate (creatinine). (GWAS Catalog, Sci Rep 2017, PMID:28452372)

G/G Published research associates this genotype with typical/baseline likelihood of Glomerular filtration rate (creatinine) — no copies of the reported risk allele. (GWAS Catalog, Sci Rep 2017, PMID:28452372)

Source: GWAS Catalog, Sci Rep 2017, PMID:28452372

Questions about rs10874312

What is rs10874312?

rs10874312 is a single position in the genome, in or near the LPHN2 gene. Published research associates it with glomerular filtration rate (creatinine). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs10874312 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs10874312 come from?

GWAS Catalog, Sci Rep 2017, PMID:28452372. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

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