0 261142315Reads by AI crawlersClaude1ChatGPT0Google · Gemini0Perplexity1Meta AI4Microsoft · Copilot0Amazon2Apple0China (ByteDance, Huawei, Baidu…)3ByteDance (Doubao)3Others15Total26Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Who was studied 25,928 European ancestry cases, 466,275 European ancestry controls, 154 East Asian ancestry cases, 178,572 East Asian ancestry controls.
The effect
Each copy of the T allele shifted the measure 0.0658 lower (95% confidence interval 0.046-0.085); p = 4 × 10−11.
Where it sits Chromosome 12, band 12q23.1 — in an intron of HAL.
What each result means
C/CNo copy of the version the research linked to Skin cancer. This is the starting point the study compared everyone against.
C/TOne copy of the version the research linked to Skin cancer. That is a smaller link than two copies.
T/TTwo copies of the version the research linked to Skin cancer. That is the strongest link of the three results. A link in a study is not a diagnosis.
rs10859996 is a single position in the genome, in or near the HAL gene. Published research associates it with skin cancer. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs10859996 linked to?
On MyGeneLog this position is linked to Sun Sensitivity, Freckling and Skin Cancer Risk. The research behind each link, and its sources, are set out on that condition page.
Does having rs10859996 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs10859996 come from?
GWAS Catalog, Nature genetics 2021, PMID:34594039. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 261142315Reads by AI crawlersClaude1ChatGPT0Google · Gemini0Perplexity1Meta AI4Microsoft · Copilot0Amazon2Apple0China (ByteDance, Huawei, Baidu…)3ByteDance (Doubao)3Others15Total26Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Quoting this page
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Skin cancer (rs10859996). MyGeneLog™. https://www.mygenelog.com/variants/rs10859996