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Height

QSOX2 · rs10858250

Where this position leads

Condition: Height

rs10858250 Condition: Height Height Condition rs10858250 rs10858250 QSOX2

What the study found

Who was studied 36,227 East Asian ancestry individuals; replicated in 57,699 East Asian ancestry individuals.

The effect Each copy of the A allele shifted the measure 0.052 lower (95% confidence interval 0.038-0.066); p = 7 × 10−23.

How common The A allele had a frequency of about 75% in the people studied.

Where it sits Chromosome 9, band 9q34.3 — in an intron of QSOX2.

What each result means

A/A Two copies of the version the research linked to Height. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to Height. That is a smaller link than two copies.
G/G No copy of the version the research linked to Height. This is the starting point the study compared everyone against.
Source
Meta-analysis of genome-wide association studies of adult height in East Asians identifies 17 novel loci
He M, Xu M, Zhang B, Liang J, Chen P, Lee JY, Johnson TA, Li H, Yang X, Dai J, Liang L, Gui L
and 79 more — show all
Qi Q, Huang J, Li Y, Adair LS, Aung T, Cai Q, Cheng CY, Cho MC, Cho YS, Chu M, Cui B, Gao YT, Go MJ, Gu D, Gu W, Guo H, Hao Y, Hong J, Hu Z, Hu Y, Huang J, Hwang JY, Ikram MK, Jin G, Kang DH, Khor CC, Kim BJ, Kim HT, Kubo M, Lee J, Lee J, Lee NR, Li R, Li J, Liu J, Longe J, Lu W, Lu X, Miao X, Okada Y, Ong RT, Qiu G, Seielstad M, Sim X, Song H, Takeuchi F, Tanaka T, Taylor PR, Wang L, Wang W, Wang Y, Wu C, Wu Y, Xiang YB, Yamamoto K, Yang H, Liao M, Yokota M, Young T, Zhang X, Kato N, Wang QK, Zheng W, Zheng W, Hu FB, Lin D, Shen H, Teo YY, Mo Z, Wong TY, Lin X, Mohlke KL, Ning G, Tsunoda T, Han BG, Shu XO, Tai ES, Wu T, Qi L
Human molecular genetics · 2015 · PMID 25429064

Questions about rs10858250

What is rs10858250?

rs10858250 is a single position in the genome, in or near the QSOX2 gene. Published research associates it with height. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs10858250 linked to?

On MyGeneLog this position is linked to Height. The research behind each link, and its sources, are set out on that condition page.

Does having rs10858250 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs10858250 come from?

GWAS Catalog, Human molecular genetics 2015, PMID:25429064. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Height (rs10858250). MyGeneLog™. https://www.mygenelog.com/variants/rs10858250

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