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Menopause (age at onset)

near NPIPB2 · rs10852344

What each result means

C/C Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Menopause (age at onset) compared to the general population. (GWAS Catalog, Nat Genet 2012, PMID:22267201)
C/T Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Menopause (age at onset). (GWAS Catalog, Nat Genet 2012, PMID:22267201)
T/T Published research associates this genotype with typical/baseline likelihood of Menopause (age at onset) — no copies of the reported risk allele. (GWAS Catalog, Nat Genet 2012, PMID:22267201)

Source: GWAS Catalog, Nat Genet 2012, PMID:22267201

Questions about rs10852344

What is rs10852344?

rs10852344 is a single position in the genome, in or near the near NPIPB2 gene. Published research associates it with menopause (age at onset). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs10852344 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs10852344 come from?

GWAS Catalog, Nat Genet 2012, PMID:22267201. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

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