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Left hippocampal volume

RNFT2 · rs10850725

What the study found

Who was studied 65,791 European ancestry, East Asian ancestry individuals.

The effect Each copy of the A allele shifted the measure 0.0472 higher (95% confidence interval 0.035-0.059); p = 7 × 10−15.

How common The A allele had a frequency of about 42% in the people studied.

Where it sits Chromosome 12, band 12q24.22 — in an intron of RNFT2.

What each result means

A/A Two copies of the version the research linked to Left hippocampal volume. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to Left hippocampal volume. That is a smaller link than two copies.
G/G No copy of the version the research linked to Left hippocampal volume. This is the starting point the study compared everyone against.
Source

Questions about rs10850725

What is rs10850725?

rs10850725 is a single position in the genome, in or near the RNFT2 gene. Published research associates it with left hippocampal volume. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs10850725 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs10850725 come from?

GWAS Catalog, Nature genetics 2023, PMID:37337106. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Left hippocampal volume (rs10850725). MyGeneLog™. https://www.mygenelog.com/variants/rs10850725

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