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Serum phosphate levels

DYRK4 · rs10849094

Where this position leads

Condition: Gout

rs10849094 Condition: Gout Gout Condition rs10849094 rs10849094 DYRK4

What the study found

Who was studied 312,888 European ancestry individuals, 5,568 African ancestry individuals, 6,685 South Asian ancestry individuals.

The effect Each copy of the G allele shifted the measure 0.0561 lower (95% confidence interval 0.046-0.066); p = 2 × 10−28.

Where it sits Chromosome 12, band 12p13.32 — in an intron of DYRK4.

What each result means

C/C No copy of the version the research linked to Serum phosphate levels. This is the starting point the study compared everyone against.
C/G One copy of the version the research linked to Serum phosphate levels. That is a smaller link than two copies.
G/G Two copies of the version the research linked to Serum phosphate levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs10849094

What is rs10849094?

rs10849094 is a single position in the genome, in or near the DYRK4 gene. Published research associates it with serum phosphate levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs10849094 linked to?

On MyGeneLog this position is linked to Gout. The research behind each link, and its sources, are set out on that condition page.

Does having rs10849094 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs10849094 come from?

GWAS Catalog, Nature genetics 2021, PMID:33462484. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Serum phosphate levels (rs10849094). MyGeneLog™. https://www.mygenelog.com/variants/rs10849094

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