near RNU6-837P · rs10846461
Where this position leads
Condition: Obesity and Body Weight
What the study found
Who was studied 507,850 East Asian ancestry individuals, 420,829 European ancestry individuals.
The effect Each copy of the T allele shifted the measure 0.0101 lower (95% confidence interval 0.0076-0.0126); p = 4 × 10−15.
Where it sits Chromosome 12, band 12p12.3 — between genes, 26.4 kb from RNU6-837P.
rs10846461 is a single position in the genome, in or near the near RNU6-837P gene. Published research associates it with weight. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
On MyGeneLog this position is linked to Obesity and Body Weight. The research behind each link, and its sources, are set out on that condition page.
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
GWAS Catalog, Nature communications 2025, PMID:40436827. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Weight (rs10846461). MyGeneLog™. https://www.mygenelog.com/variants/rs10846461