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Neutrophil-to-lymphocyte ratio

near CD69 · rs10844750

What the study found

Who was studied 234,502 European ancestry individuals; replicated in 100,442 European ancestry individuals.

The effect The reported allele is C; the catalogue records no effect size ; p = 9 × 10−75.

How common The C allele had a frequency of about 73% in the people studied.

Where it sits Chromosome 12, band 12p13.31 — between genes, 13.4 kb from CD69.

What each result means

C/C Two copies of the version the research linked to Neutrophil-to-lymphocyte ratio. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/T One copy of the version the research linked to Neutrophil-to-lymphocyte ratio. That is a smaller link than two copies.
T/T No copy of the version the research linked to Neutrophil-to-lymphocyte ratio. This is the starting point the study compared everyone against.
Source

Questions about rs10844750

What is rs10844750?

rs10844750 is a single position in the genome, in or near the near CD69 gene. Published research associates it with neutrophil-to-lymphocyte ratio. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs10844750 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs10844750 come from?

GWAS Catalog, American journal of human genetics 2021, PMID:34469753. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Neutrophil-to-lymphocyte ratio (rs10844750). MyGeneLog™. https://www.mygenelog.com/variants/rs10844750

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