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Glioma

STK38L · rs10842893

Where this position leads

Condition: Glioma

rs10842893 Condition: Glioma Glioma Condition rs10842893 rs10842893 STK38L

What the study found

Who was studied 992 Han Chinese ancestry cases, 1,008 Han Chinese ancestry controls; replicated in 2,105 Han Chinese ancestry cases, 3,374 Han Chinese ancestry controls.

The effect Each copy of the T allele carried 2.07 times the odds of Glioma (95% confidence interval 1.71-2.50); p = 2 × 10−12.

How common The T allele had a frequency of about 2% in the people studied.

Where it sits Chromosome 12, band 12p11.23 — in an intron of STK38L.

What each result means

C/C No copy of the version the research linked to Glioma. This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to Glioma. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Glioma. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs10842893

What is rs10842893?

rs10842893 is a single position in the genome, in or near the STK38L gene. Published research associates it with glioma. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs10842893 linked to?

On MyGeneLog this position is linked to Glioma. The research behind each link, and its sources, are set out on that condition page.

Does having rs10842893 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs10842893 come from?

GWAS Catalog, International journal of cancer 2019, PMID:30714141. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Glioma (rs10842893). MyGeneLog™. https://www.mygenelog.com/variants/rs10842893

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