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Concentration of medium LDL particles

near HNRNPA1P34 · rs10842724

What the study found

Who was studied 115,082 European ancestry individuals.

The effect Each copy of the T allele shifted the measure 0.0259 lower (95% confidence interval 0.018-0.034); p = 8 × 10−10.

How common The T allele had a frequency of about 59% in the people studied.

Where it sits Chromosome 12, band 12p13.31 — between genes, 7.5 kb from HNRNPA1P34.

What each result means

C/C Published research associates this genotype with typical/baseline likelihood of Concentration of medium LDL particles — no copies of the reported risk allele.
C/T Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Concentration of medium LDL particles.
T/T Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Concentration of medium LDL particles compared to the general population.
Source

Questions about rs10842724

What is rs10842724?

rs10842724 is a single position in the genome, in or near the near HNRNPA1P34 gene. Published research associates it with concentration of medium ldl particles. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs10842724 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs10842724 come from?

GWAS Catalog, PLoS biology 2022, PMID:35213538. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Concentration of medium LDL particles (rs10842724). MyGeneLog™. https://www.mygenelog.com/variants/rs10842724

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