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Aortic valve mean gradient

near LINC02468 · rs10841441

What the study found

Who was studied 59,571 European ancestry individuals.

The effect Each copy of the C allele shifted the measure 0.0438 higher (95% confidence interval 0.032-0.056); p = 2 × 10−12.

How common The C allele had a frequency of about 30% in the people studied.

Where it sits Chromosome 12, band 12p12.2 — between genes, 63.3 kb from LINC02468.

What each result means

C/C Two copies of the version the research linked to Aortic valve mean gradient. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/T One copy of the version the research linked to Aortic valve mean gradient. That is a smaller link than two copies.
T/T No copy of the version the research linked to Aortic valve mean gradient. This is the starting point the study compared everyone against.
Source

Questions about rs10841441

What is rs10841441?

rs10841441 is a single position in the genome, in or near the near LINC02468 gene. Published research associates it with aortic valve mean gradient. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs10841441 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs10841441 come from?

GWAS Catalog, Nature genetics 2026, PMID:41419685. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Aortic valve mean gradient (rs10841441). MyGeneLog™. https://www.mygenelog.com/variants/rs10841441

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