Standard
High density lipoprotein cholesterol levels
MADD · rs10838692
Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What each result means
C/C
Published research associates this genotype with typical/baseline likelihood of High density lipoprotein cholesterol levels — no copies of the reported risk allele.
C/T
Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with High density lipoprotein cholesterol levels.
T/T
Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of High density lipoprotein cholesterol levels compared to the general population.
Source
A large electronic-health-record-based genome-wide study of serum lipids
Hoffmann TJ,
Theusch E,
Haldar T,
Ranatunga DK,
Jorgenson E,
Medina MW,
Kvale MN,
Kwok PY,
Schaefer C,
Krauss RM,
Iribarren C,
Risch N
Nature genetics · 2018 · PMID 29507422 · open access
Questions about rs10838692
What is rs10838692?
rs10838692 is a single position in the genome, in or near the MADD gene. Published research associates it with high density lipoprotein cholesterol levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs10838692 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs10838692 come from?
GWAS Catalog, Nat Genet 2018, PMID:29507422. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
← See all variants