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Who was studied 13,047 European ancestry cases, 262,499 European ancestry controls; replicated in 4,450 European ancestry cases, 87,398 European ancestry controls.
The effect
The reported allele is C; the catalogue records no effect size
; p = 9 × 10−13.
How common The C allele had a frequency of about 79% in the people studied.
Where it sits Chromosome 11, band 11p13 — in an intron of PRRG4.
What each result means
C/CTwo copies of the version the research linked to Inguinal hernia. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/TOne copy of the version the research linked to Inguinal hernia. That is a smaller link than two copies.
T/TNo copy of the version the research linked to Inguinal hernia. This is the starting point the study compared everyone against.
Hernia : the journal of hernias and abdominal wall surgery · 2022 · PMID 34382107
Questions about rs10835981
What is rs10835981?
rs10835981 is a single position in the genome, in or near the PRRG4 gene. Published research associates it with inguinal hernia. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs10835981 linked to?
On MyGeneLog this position is linked to Inguinal Hernia. The research behind each link, and its sources, are set out on that condition page.
Does having rs10835981 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs10835981 come from?
GWAS Catalog, Hernia : the journal of hernias and abdominal wall surgery 2022, PMID:34382107. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 91215Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity1Meta AI0Microsoft · Copilot0Amazon2Apple1China (ByteDance, Huawei, Baidu…)0Others5Total9Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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