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Mitochondrial DNA levels

STIM1 · rs10835226

What the study found

Who was studied 295,150 European ancestry individuals.

The effect Each copy of the T allele shifted the measure 0.0178 higher (95% confidence interval 0.012-0.023); p = 5 × 10−10.

How common The T allele had a frequency of about 32% in the people studied.

Where it sits Chromosome 11, band 11p15.4 — in an intron of STIM1.

What each result means

C/C No copy of the version the research linked to Mitochondrial DNA levels. This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to Mitochondrial DNA levels. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Mitochondrial DNA levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs10835226

What is rs10835226?

rs10835226 is a single position in the genome, in or near the STIM1 gene. Published research associates it with mitochondrial dna levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs10835226 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs10835226 come from?

GWAS Catalog, Human genetics 2021, PMID:33385171. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Mitochondrial DNA levels (rs10835226). MyGeneLog™. https://www.mygenelog.com/variants/rs10835226

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