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Body size or adipose distribution (multivariate analysis)

PALD1 · rs10823589

What the study found

Who was studied 690,110 European ancestry individuals.

The effect Each copy of the G allele shifted the measure 0.0109 lower (95% confidence interval 0.0072-0.0146); p = 1 × 10−8.

Where it sits Chromosome 10, band 10q22.1 — inside PALD1.

What each result means

A/A No copy of the version the research linked to Body size or adipose distribution (multivariate analysis). This is the starting point the study compared everyone against.
A/G One copy of the version the research linked to Body size or adipose distribution (multivariate analysis). That is a smaller link than two copies.
G/G Two copies of the version the research linked to Body size or adipose distribution (multivariate analysis). That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs10823589

What is rs10823589?

rs10823589 is a single position in the genome, in or near the PALD1 gene. Published research associates it with body size or adipose distribution (multivariate analysis). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs10823589 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs10823589 come from?

GWAS Catalog, Nature communications 2025, PMID:40796553. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Body size or adipose distribution (multivariate analysis) (rs10823589). MyGeneLog™. https://www.mygenelog.com/variants/rs10823589

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