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Atrial fibrillation/atrial flutter

CTNNA3 · rs10823051

Where this position leads

Condition: Atrial Fibrillation

rs10823051 Condition: Atrial Fibrillation Atrial Fibrillation Condition rs10823051 rs10823051 CTNNA3

What the study found

Who was studied 29,212 European ancestry cases, 400,539 European ancestry controls, 4,150 East Asian ancestry cases, 155,540 East Asian ancestry controls.

The effect Each copy of the C allele shifted the measure 0.08 higher (95% confidence interval 0.055-0.105); p = 2 × 10−10.

Where it sits Chromosome 10, band 10q21.3 — in an intron of CTNNA3.

What each result means

C/C Two copies of the version the research linked to Atrial fibrillation/atrial flutter. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/G One copy of the version the research linked to Atrial fibrillation/atrial flutter. That is a smaller link than two copies.
G/G No copy of the version the research linked to Atrial fibrillation/atrial flutter. This is the starting point the study compared everyone against.
Source

Questions about rs10823051

What is rs10823051?

rs10823051 is a single position in the genome, in or near the CTNNA3 gene. Published research associates it with atrial fibrillation/atrial flutter. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs10823051 linked to?

On MyGeneLog this position is linked to Atrial Fibrillation. The research behind each link, and its sources, are set out on that condition page.

Does having rs10823051 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs10823051 come from?

GWAS Catalog, Nature genetics 2021, PMID:34594039. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Atrial fibrillation/atrial flutter (rs10823051). MyGeneLog™. https://www.mygenelog.com/variants/rs10823051

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