Sensitive

Basal cell carcinoma (MTAG)

near SMC2 · rs10820610

Where this position leads

Condition: Basal Cell Carcinoma

rs10820610 Condition: Basal Cell Carcinoma Basal Cell Carcinoma Condition rs10820610 rs10820610 near SMC2

What the study found

Who was studied 20,791 European ancestry cases, 286,893 European ancestry controls; replicated in 251,963 European ancestry cases, 2,271,667 European ancestry controls.

The effect The reported allele is A; the catalogue records no effect size ; p = 4 × 10−30.

Where it sits Chromosome 9, band 9q31.1 — between genes, 1.1 kb from SMC2.

What each result means

A/A Two copies of the version the research linked to Basal cell carcinoma (MTAG). That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to Basal cell carcinoma (MTAG). That is a smaller link than two copies.
G/G No copy of the version the research linked to Basal cell carcinoma (MTAG). This is the starting point the study compared everyone against.
Source

Questions about rs10820610

What is rs10820610?

rs10820610 is a single position in the genome, in or near the near SMC2 gene. Published research associates it with basal cell carcinoma (mtag). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs10820610 linked to?

On MyGeneLog this position is linked to Basal Cell Carcinoma. The research behind each link, and its sources, are set out on that condition page.

Does having rs10820610 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs10820610 come from?

GWAS Catalog, Nature communications 2022, PMID:36496446. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Basal cell carcinoma (MTAG) (rs10820610). MyGeneLog™. https://www.mygenelog.com/variants/rs10820610

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