Developmental dysplasia of the hip or hip osteoarthritis
ASTN2 · rs10817926
0 422Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot0Amazon2Apple0China (ByteDance, Huawei, Baidu…)0Others2Total4Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Who was studied 36,445 European ancestry cases, 316,943 European ancestry controls, 1,085 Japanese ancestry cases, 24,000 Japanese ancestry controls.
The effect
Each copy of the A allele carried 0.93 times the odds of Developmental dysplasia of the hip or hip osteoarthritis (95% confidence interval 0.914-0.947); p = 5 × 10−16.
How common The A allele had a frequency of about 46% in the people studied.
Where it sits Chromosome 9, band 9q33.1 — in an intron of ASTN2.
What each result means
A/ATwo copies of the version the research linked to Developmental dysplasia of the hip or hip osteoarthritis. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/COne copy of the version the research linked to Developmental dysplasia of the hip or hip osteoarthritis. That is a smaller link than two copies.
C/CNo copy of the version the research linked to Developmental dysplasia of the hip or hip osteoarthritis. This is the starting point the study compared everyone against.
Bone research · 2026 · PMID 41912496 · open access
Questions about rs10817926
What is rs10817926?
rs10817926 is a single position in the genome, in or near the ASTN2 gene. Published research associates it with developmental dysplasia of the hip or hip osteoarthritis. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs10817926 linked to?
On MyGeneLog this position is linked to Hip Osteoarthritis. The research behind each link, and its sources, are set out on that condition page.
Does having rs10817926 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs10817926 come from?
GWAS Catalog, Bone research 2026, PMID:41912496. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 422Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot0Amazon2Apple0China (ByteDance, Huawei, Baidu…)0Others2Total4Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Quoting this page
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Developmental dysplasia of the hip or hip osteoarthritis (rs10817926). MyGeneLog™. https://www.mygenelog.com/variants/rs10817926