Sensitive

Crohn's disease

near TNFSF15 · rs10817678

Where this position leads

Condition: Crohn's Disease

rs10817678 Condition: Crohn's Disease Crohn's Disease Condition rs10817678 rs10817678 near TNFSF15

What the study found

Who was studied 1,621 Korean ancestry cases, 4,419 Korean ancestry controls; replicated in 738 Korean ancestry cases, 488 Korean ancestry controls.

The effect The reported allele is A; the catalogue records no effect size ; p = 1 × 10−76.

Where it sits Chromosome 9, band 9q32 — between genes, 11.1 kb from TNFSF15.

What each result means

A/A Two copies of the version the research linked to Crohn's disease. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to Crohn's disease. That is a smaller link than two copies.
G/G No copy of the version the research linked to Crohn's disease. This is the starting point the study compared everyone against.
Source

Questions about rs10817678

What is rs10817678?

rs10817678 is a single position in the genome, in or near the near TNFSF15 gene. Published research associates it with crohn's disease. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs10817678 linked to?

On MyGeneLog this position is linked to Crohn's Disease. The research behind each link, and its sources, are set out on that condition page.

Does having rs10817678 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs10817678 come from?

GWAS Catalog, Human molecular genetics 2022, PMID:35512355. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Crohn's disease (rs10817678). MyGeneLog™. https://www.mygenelog.com/variants/rs10817678

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