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Uterine fibroids

KANK1-AS1 · rs10815466

Where this position leads

Condition: Uterine Fibroids

rs10815466 Condition: Uterine Fibroids Uterine Fibroids Condition rs10815466 rs10815466 KANK1-AS1

What the study found

Who was studied 53,711 European ancestry female cases, 380,441 European ancestry female controls.

The effect Each copy of the A allele shifted the measure 0.102 higher (95% confidence interval 0.085-0.12); p = 3 × 10−30.

Where it sits Chromosome 9, band 9p24.3 — in an intron of KANK1-AS1.

What each result means

A/A Two copies of the version the research linked to Uterine fibroids. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to Uterine fibroids. That is a smaller link than two copies.
G/G No copy of the version the research linked to Uterine fibroids. This is the starting point the study compared everyone against.
Source

Questions about rs10815466

What is rs10815466?

rs10815466 is a single position in the genome, in or near the KANK1-AS1 gene. Published research associates it with uterine fibroids. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs10815466 linked to?

On MyGeneLog this position is linked to Uterine Fibroids. The research behind each link, and its sources, are set out on that condition page.

Does having rs10815466 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs10815466 come from?

GWAS Catalog, Nature communications 2025, PMID:40050615. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Uterine fibroids (rs10815466). MyGeneLog™. https://www.mygenelog.com/variants/rs10815466

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