Standard
Mean platelet volume
DOCK8 · rs10813766
Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What each result means
G/G
Published research associates this genotype with typical/baseline likelihood of Mean platelet volume — no copies of the reported risk allele.
G/T
Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Mean platelet volume.
T/T
Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Mean platelet volume compared to the general population.
Source
New gene functions in megakaryopoiesis and platelet formation
Gieger C,
Radhakrishnan A,
Cvejic A,
Tang W,
Porcu E,
Pistis G,
Serbanovic-Canic J,
Elling U,
Goodall AH,
Labrune Y,
Lopez LM,
Mägi R
and 151 more — show all
Meacham S,
Okada Y,
Pirastu N,
Sorice R,
Teumer A,
Voss K,
Zhang W,
Ramirez-Solis R,
Bis JC,
Ellinghaus D,
Gögele M,
Hottenga JJ,
Langenberg C,
Kovacs P,
O'Reilly PF,
Shin SY,
Esko T,
Hartiala J,
Kanoni S,
Murgia F,
Parsa A,
Stephens J,
van der Harst P,
Ellen van der Schoot C,
Allayee H,
Attwood A,
Balkau B,
Bastardot F,
Basu S,
Baumeister SE,
Biino G,
Bomba L,
Bonnefond A,
Cambien F,
Chambers JC,
Cucca F,
D'Adamo P,
Davies G,
de Boer RA,
de Geus EJ,
Döring A,
Elliott P,
Erdmann J,
Evans DM,
Falchi M,
Feng W,
Folsom AR,
Frazer IH,
Gibson QD,
Glazer NL,
Hammond C,
Hartikainen AL,
Heckbert SR,
Hengstenberg C,
Hersch M,
Illig T,
Loos RJ,
Jolley J,
Khaw KT,
Kühnel B,
Kyrtsonis MC,
Lagou V,
Lloyd-Jones H,
Lumley T,
Mangino M,
Maschio A,
Mateo Leach I,
McKnight B,
Memari Y,
Mitchell BD,
Montgomery GW,
Nakamura Y,
Nauck M,
Navis G,
Nöthlings U,
Nolte IM,
Porteous DJ,
Pouta A,
Pramstaller PP,
Pullat J,
Ring SM,
Rotter JI,
Ruggiero D,
Ruokonen A,
Sala C,
Samani NJ,
Sambrook J,
Schlessinger D,
Schreiber S,
Schunkert H,
Scott J,
Smith NL,
Snieder H,
Starr JM,
Stumvoll M,
Takahashi A,
Tang WH,
Taylor K,
Tenesa A,
Lay Thein S,
Tönjes A,
Uda M,
Ulivi S,
van Veldhuisen DJ,
Visscher PM,
Völker U,
Wichmann HE,
Wiggins KL,
Willemsen G,
Yang TP,
Hua Zhao J,
Zitting P,
Bradley JR,
Dedoussis GV,
Gasparini P,
Hazen SL,
Metspalu A,
Pirastu M,
Shuldiner AR,
Joost van Pelt L,
Zwaginga JJ,
Boomsma DI,
Deary IJ,
Franke A,
Froguel P,
Ganesh SK,
Jarvelin MR,
Martin NG,
Meisinger C,
Psaty BM,
Spector TD,
Wareham NJ,
Akkerman JW,
Ciullo M,
Deloukas P,
Greinacher A,
Jupe S,
Kamatani N,
Khadake J,
Kooner JS,
Penninger J,
Prokopenko I,
Stemple D,
Toniolo D,
Wernisch L,
Sanna S,
Hicks AA,
Rendon A,
Ferreira MA,
Ouwehand WH,
Soranzo N
Nature · 2011 · PMID 22139419
Questions about rs10813766
What is rs10813766?
rs10813766 is a single position in the genome, in or near the DOCK8 gene. Published research associates it with mean platelet volume. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs10813766 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs10813766 come from?
GWAS Catalog, Nature 2011, PMID:22139419. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
← See all variants