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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 14,382 European ancestry individuals, 1,279 non-European ancestry individuals.
The effect
Each copy of the C allele shifted the measure 0.203 higher (95% confidence interval 0.13-0.27); p = 2 × 10−8.
How common The C allele had a frequency of about 51% in the people studied.
Where it sits Chromosome 16, band 16q12.1 — between genes, 53.1 kb from LOC124903765.
What each result means
C/CTwo copies of the version the research linked to Digit length ratio (left hand). That is the strongest link of the three results. A link in a study is not a diagnosis.
C/TOne copy of the version the research linked to Digit length ratio (left hand). That is a smaller link than two copies.
T/TNo copy of the version the research linked to Digit length ratio (left hand). This is the starting point the study compared everyone against.
Human molecular genetics · 2018 · PMID 29659830 · open access
Questions about rs1080014
What is rs1080014?
rs1080014 is a single position in the genome, in or near the TOX3 gene. Published research associates it with digit length ratio (left hand). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs1080014 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs1080014 come from?
GWAS Catalog, Hum Mol Genet 2018, PMID:29659830. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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Quoting this page
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Digit length ratio (left hand) (rs1080014). MyGeneLog™. https://www.mygenelog.com/variants/rs1080014