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Who was studied 394,626 European ancestry individuals.
The effect
Each copy of the A allele shifted the measure 0.206 lower (95% confidence interval 0.15-0.27); p = 7 × 10−12.
How common The A allele had a frequency of about 57% in the people studied.
Where it sits Chromosome 1, band 1p36.13 — between genes, 4.9 kb from RNF186.
What each result means
A/ATwo copies of the version the research linked to Ulcerative colitis. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/GOne copy of the version the research linked to Ulcerative colitis. That is a smaller link than two copies.
G/GNo copy of the version the research linked to Ulcerative colitis. This is the starting point the study compared everyone against.
Nature genetics · 2025 · PMID 39789286 · open access
Questions about rs10799837
What is rs10799837?
rs10799837 is a single position in the genome, in or near the near RNF186 gene. Published research associates it with ulcerative colitis. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs10799837 linked to?
On MyGeneLog this position is linked to Ulcerative Colitis. The research behind each link, and its sources, are set out on that condition page.
Does having rs10799837 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs10799837 come from?
GWAS Catalog, Nature genetics 2025, PMID:39789286. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 6123Reads by AI crawlersClaude1ChatGPT0Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot0Amazon2Apple0China (ByteDance, Huawei, Baidu…)0Others3Total6Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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