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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 1,167 European ancestry opioid-dependent daily injector cases, 161 European ancestry opioid misusers (impeded progression) controls; replicated in 833 European ancestry opioid-dependent daily injector cases, 476 European ancestry opioid misusers (impeded progression) controls.
The effect
Each copy of the G allele carried 1.56 times the odds of Opioid dependence (95% confidence interval 1.35-1.82); p = 4 × 10−9.
How common The G allele had a frequency of about 49% in the people studied.
Where it sits Chromosome 1, band 1q42.12 — in an intron of CNIH3.
What each result means
A/ANo copy of the version the research linked to Opioid dependence. This is the starting point the study compared everyone against.
A/GOne copy of the version the research linked to Opioid dependence. That is a smaller link than two copies.
G/GTwo copies of the version the research linked to Opioid dependence. That is the strongest link of the three results. A link in a study is not a diagnosis.
Molecular psychiatry · 2016 · PMID 26239289 · open access
Questions about rs10799590
What is rs10799590?
rs10799590 is a single position in the genome, in or near the CNIH3 gene. Published research associates it with opioid dependence. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs10799590 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs10799590 come from?
GWAS Catalog, Molecular psychiatry 2016, PMID:26239289. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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