Sensitive

Colorectal cancer

GATA3 · rs10795668

Where this position leads

Condition: Colorectal Cancer

rs10795668 Condition: Colorectal Cancer Colorectal Cancer Condition rs10795668 rs10795668 GATA3

What the study found

Who was studied 23,572 East Asian ancestry cases, 48,700 East Asian ancestry controls; replicated in 58,131 European ancestry cases, 67,347 European ancestry controls.

The effect Each copy of the G allele carried 1.14 times the odds of Colorectal cancer (95% confidence interval 1.11-1.17); p = 1 × 10−23.

Where it sits Chromosome 10, band 10p14 — inside LOC105376400.

What each result means

A/A No copy of the version the research linked to Colorectal cancer. This is the starting point the study compared everyone against.
A/G One copy of the version the research linked to Colorectal cancer. That is a smaller link than two copies.
G/G Two copies of the version the research linked to Colorectal cancer. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

What people read about alongside this

Papers in Europe PMC whose title or abstract names both this rsID and that subject. A shared paper means somebody wrote about the two together — it is not a claim that this position explains the subject.

Questions about rs10795668

What is rs10795668?

rs10795668 is a single position in the genome, in or near the GATA3 gene. Published research associates it with colorectal cancer. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs10795668 linked to?

On MyGeneLog this position is linked to Colorectal Cancer. The research behind each link, and its sources, are set out on that condition page.

What do people read about alongside rs10795668?

Subjects that appear in the title or abstract of the same papers as this rsID include blood sugar and insulin (1 papers). A shared paper means somebody wrote about the two together; it is not a claim that this position explains the topic.

Does having rs10795668 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs10795668 come from?

GWAS Catalog, Cancer Epidemiol Biomarkers Prev 2019, PMID:31826910. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Colorectal cancer (rs10795668). MyGeneLog™. https://www.mygenelog.com/variants/rs10795668

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