Uterine leiomyoma or ER negative breast cancer (pleiotropy)
POGLUT3 · rs10789665
1 523Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot0Amazon2Apple0China (ByteDance, Huawei, Baidu…)0Others3Total5Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Who was studied 35,474 European ancestry UL cases, 21,468 European ancestry ER-ve BC cases, 373,479 European ancestry controls.
The effect
The reported allele is T; the catalogue records no effect size
; p = 3 × 10−14.
Where it sits Chromosome 11, band 11q22.3 — in an intron of POGLUT3.
What each result means
C/CNo copy of the version the research linked to Uterine leiomyoma or ER negative breast cancer (pleiotropy). This is the starting point the study compared everyone against.
C/TOne copy of the version the research linked to Uterine leiomyoma or ER negative breast cancer (pleiotropy). That is a smaller link than two copies.
T/TTwo copies of the version the research linked to Uterine leiomyoma or ER negative breast cancer (pleiotropy). That is the strongest link of the three results. A link in a study is not a diagnosis.
American journal of human genetics · 2022 · PMID 35803233
Questions about rs10789665
What is rs10789665?
rs10789665 is a single position in the genome, in or near the POGLUT3 gene. Published research associates it with uterine leiomyoma or er negative breast cancer (pleiotropy). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs10789665 linked to?
On MyGeneLog this position is linked to Breast Cancer. The research behind each link, and its sources, are set out on that condition page.
Does having rs10789665 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs10789665 come from?
GWAS Catalog, American journal of human genetics 2022, PMID:35803233. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
1 523Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot0Amazon2Apple0China (ByteDance, Huawei, Baidu…)0Others3Total5Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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Uterine leiomyoma or ER negative breast cancer (pleiotropy) (rs10789665). MyGeneLog™. https://www.mygenelog.com/variants/rs10789665