Standard

Waist-hip ratio

CFL1P1 · rs10788569

Where this position leads

Condition: Waist-to-Hip Ratio (Body Fat Distribution)

rs10788569 Condition: Waist-to-Hip Ratio (Body Fat Distribution) Waist-to-Hip Ratio (Body Fat Distri… Condition rs10788569 rs10788569 CFL1P1

What the study found

Who was studied 381,152 European female individuals.

The effect Each copy of the T allele shifted the measure 0.0134 lower (95% confidence interval 0.0097-0.0171); p = 4 × 10−12.

How common The T allele had a frequency of about 72% in the people studied.

Where it sits Chromosome 10, band 10q23.31 — in a non-coding transcript of CFL1P1.

What each result means

C/C No copy of the version the research linked to Waist-hip ratio. This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to Waist-hip ratio. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Waist-hip ratio. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs10788569

What is rs10788569?

rs10788569 is a single position in the genome, in or near the CFL1P1 gene. Published research associates it with waist-hip ratio. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs10788569 linked to?

On MyGeneLog this position is linked to Waist-to-Hip Ratio (Body Fat Distribution). The research behind each link, and its sources, are set out on that condition page.

Does having rs10788569 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs10788569 come from?

GWAS Catalog, Human molecular genetics 2019, PMID:30239722. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

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Waist-hip ratio (rs10788569). MyGeneLog™. https://www.mygenelog.com/variants/rs10788569

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