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Who was studied 2,523 Korean ancestry cases, 76,598 Korean ancestry controls.
The effect
Each copy of the A allele carried 1.33 times the odds of Crohn's disease (95% confidence interval 1.23-1.44); p = 1 × 10−12.
How common The A allele had a frequency of about 30% in the people studied.
Where it sits Chromosome 10, band 10q24.2 — between genes, 18.9 kb from NKX2-3.
What each result means
A/ATwo copies of the version the research linked to Crohn's disease. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/GOne copy of the version the research linked to Crohn's disease. That is a smaller link than two copies.
G/GNo copy of the version the research linked to Crohn's disease. This is the starting point the study compared everyone against.
Journal of Crohn's & colitis · 2024 · PMID 37523193
Questions about rs10786560
What is rs10786560?
rs10786560 is a single position in the genome, in or near the near NKX2-3 gene. Published research associates it with crohn's disease. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs10786560 linked to?
On MyGeneLog this position is linked to Crohn's Disease. The research behind each link, and its sources, are set out on that condition page.
Does having rs10786560 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs10786560 come from?
GWAS Catalog, Journal of Crohn's & colitis 2024, PMID:37523193. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 8224Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot0Amazon2Apple0China (ByteDance, Huawei, Baidu…)2ByteDance (Doubao)2Others4Total8Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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