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3-hydroxy-2-ethylpropionate levels

near CYP2C8 · rs10786187

What the study found

Who was studied 8,238 European ancestry individuals.

The effect Each copy of the G allele shifted the measure 0.129 higher (95% confidence interval 0.099-0.16); p = 5 × 10−17.

How common The G allele had a frequency of about 56% in the people studied.

Where it sits Chromosome 10, band 10q23.33 — between genes, 26.8 kb from CYP2C8.

What each result means

A/A No copy of the version the research linked to 3-hydroxy-2-ethylpropionate levels. This is the starting point the study compared everyone against.
A/G One copy of the version the research linked to 3-hydroxy-2-ethylpropionate levels. That is a smaller link than two copies.
G/G Two copies of the version the research linked to 3-hydroxy-2-ethylpropionate levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs10786187

What is rs10786187?

rs10786187 is a single position in the genome, in or near the near CYP2C8 gene. Published research associates it with 3-hydroxy-2-ethylpropionate levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs10786187 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs10786187 come from?

GWAS Catalog, Nature genetics 2023, PMID:36635386. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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3-hydroxy-2-ethylpropionate levels (rs10786187). MyGeneLog™. https://www.mygenelog.com/variants/rs10786187

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