Standard
Brain structure
HMGA2 · rs10784502
Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What each result means
C/C
Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Brain structure compared to the general population.
C/T
Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Brain structure.
T/T
Published research associates this genotype with typical/baseline likelihood of Brain structure — no copies of the reported risk allele.
Source
Identification of common variants associated with human hippocampal and intracranial volumes
Stein JL,
Medland SE,
Vasquez AA,
Hibar DP,
Senstad RE,
Winkler AM,
Toro R,
Appel K,
Bartecek R,
Bergmann Ø,
Bernard M,
Brown AA
and 190 more — show all
Cannon DM,
Chakravarty MM,
Christoforou A,
Domin M,
Grimm O,
Hollinshead M,
Holmes AJ,
Homuth G,
Hottenga JJ,
Langan C,
Lopez LM,
Hansell NK,
Hwang KS,
Kim S,
Laje G,
Lee PH,
Liu X,
Loth E,
Lourdusamy A,
Mattingsdal M,
Mohnke S,
Maniega SM,
Nho K,
Nugent AC,
O'Brien C,
Papmeyer M,
Pütz B,
Ramasamy A,
Rasmussen J,
Rijpkema M,
Risacher SL,
Roddey JC,
Rose EJ,
Ryten M,
Shen L,
Sprooten E,
Strengman E,
Teumer A,
Trabzuni D,
Turner J,
van Eijk K,
van Erp TG,
van Tol MJ,
Wittfeld K,
Wolf C,
Woudstra S,
Aleman A,
Alhusaini S,
Almasy L,
Binder EB,
Brohawn DG,
Cantor RM,
Carless MA,
Corvin A,
Czisch M,
Curran JE,
Davies G,
de Almeida MA,
Delanty N,
Depondt C,
Duggirala R,
Dyer TD,
Erk S,
Fagerness J,
Fox PT,
Freimer NB,
Gill M,
Göring HH,
Hagler DJ,
Hoehn D,
Holsboer F,
Hoogman M,
Hosten N,
Jahanshad N,
Johnson MP,
Kasperaviciute D,
Kent JW Jr,
Kochunov P,
Lancaster JL,
Lawrie SM,
Liewald DC,
Mandl R,
Matarin M,
Mattheisen M,
Meisenzahl E,
Melle I,
Moses EK,
Mühleisen TW,
Nauck M,
Nöthen MM,
Olvera RL,
Pandolfo M,
Pike GB,
Puls R,
Reinvang I,
Rentería ME,
Rietschel M,
Roffman JL,
Royle NA,
Rujescu D,
Savitz J,
Schnack HG,
Schnell K,
Seiferth N,
Smith C,
Steen VM,
Valdés Hernández MC,
Van den Heuvel M,
van der Wee NJ,
Van Haren NE,
Veltman JA,
Völzke H,
Walker R,
Westlye LT,
Whelan CD,
Agartz I,
Boomsma DI,
Cavalleri GL,
Dale AM,
Djurovic S,
Drevets WC,
Hagoort P,
Hall J,
Heinz A,
Jack CR Jr,
Foroud TM,
Le Hellard S,
Macciardi F,
Montgomery GW,
Poline JB,
Porteous DJ,
Sisodiya SM,
Starr JM,
Sussmann J,
Toga AW,
Veltman DJ,
Walter H,
Weiner MW,
Bis JC,
Ikram MA,
Smith AV,
Gudnason V,
Tzourio C,
Vernooij MW,
Launer LJ,
DeCarli C,
Seshadri S,
Andreassen OA,
Apostolova LG,
Bastin ME,
Blangero J,
Brunner HG,
Buckner RL,
Cichon S,
Coppola G,
de Zubicaray GI,
Deary IJ,
Donohoe G,
de Geus EJ,
Espeseth T,
Fernández G,
Glahn DC,
Grabe HJ,
Hardy J,
Hulshoff Pol HE,
Jenkinson M,
Kahn RS,
McDonald C,
McIntosh AM,
McMahon FJ,
McMahon KL,
Meyer-Lindenberg A,
Morris DW,
Müller-Myhsok B,
Nichols TE,
Ophoff RA,
Paus T,
Pausova Z,
Penninx BW,
Potkin SG,
Sämann PG,
Saykin AJ,
Schumann G,
Smoller JW,
Wardlaw JM,
Weale ME,
Martin NG,
Franke B,
Wright MJ,
Thompson PM
Nature genetics · 2012 · PMID 22504417
What people read about alongside this
Papers in Europe PMC whose title or abstract names both this rsID and that subject. A shared paper means somebody wrote about the two together — it is not a claim that this position explains the subject.
Questions about rs10784502
What is rs10784502?
rs10784502 is a single position in the genome, in or near the HMGA2 gene. Published research associates it with brain structure. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What do people read about alongside rs10784502?
Subjects that appear in the title or abstract of the same papers as this rsID include brain and memory (1 papers). A shared paper means somebody wrote about the two together; it is not a claim that this position explains the topic.
Does having rs10784502 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs10784502 come from?
GWAS Catalog, Nat Genet 2012, PMID:22504417. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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