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Corneal resistance factor (MTAG)

near CFAP95 · rs10780724

What the study found

Who was studied 123,734 European ancestry individuals.

The effect Each copy of the T allele shifted the measure 0.0673 lower (95% confidence interval 0.055-0.079); p = 3 × 10−28.

How common The T allele had a frequency of about 11% in the people studied.

Where it sits Chromosome 9, band 9q21.12 — between genes, 44.2 kb from CFAP95.

What each result means

C/C No copy of the version the research linked to Corneal resistance factor (MTAG). This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to Corneal resistance factor (MTAG). That is a smaller link than two copies.
T/T Two copies of the version the research linked to Corneal resistance factor (MTAG). That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs10780724

What is rs10780724?

rs10780724 is a single position in the genome, in or near the near CFAP95 gene. Published research associates it with corneal resistance factor (mtag). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs10780724 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs10780724 come from?

GWAS Catalog, JAMA ophthalmology 2022, PMID:35446358. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Corneal resistance factor (MTAG) (rs10780724). MyGeneLog™. https://www.mygenelog.com/variants/rs10780724

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