Sensitive

Type 2 diabetes

near RN7SKP15 · rs10771372

Where this position leads

Condition: Type 2 Diabetes

rs10771372 Condition: Type 2 Diabetes Type 2 Diabetes Condition rs10771372 rs10771372 near RN7SKP15

What the study found

Who was studied 148,726 European ancestry cases, 965,732 European ancestry controls.

The effect Each copy of the C allele shifted the measure 0.0721 higher (95% confidence interval 0.061-0.083); p = 2 × 10−35.

How common The C allele had a frequency of about 80% in the people studied.

Where it sits Chromosome 12, band 12p11.22 — between genes, 2.9 kb from RN7SKP15.

What each result means

C/C Two copies of the version the research linked to Type 2 diabetes. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/T One copy of the version the research linked to Type 2 diabetes. That is a smaller link than two copies.
T/T No copy of the version the research linked to Type 2 diabetes. This is the starting point the study compared everyone against.
Source

Questions about rs10771372

What is rs10771372?

rs10771372 is a single position in the genome, in or near the near RN7SKP15 gene. Published research associates it with type 2 diabetes. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs10771372 linked to?

On MyGeneLog this position is linked to Type 2 Diabetes. The research behind each link, and its sources, are set out on that condition page.

Does having rs10771372 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs10771372 come from?

GWAS Catalog, Nature genetics 2020, PMID:32541925. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Type 2 diabetes (rs10771372). MyGeneLog™. https://www.mygenelog.com/variants/rs10771372

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