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Retinal detachment or retinal break

FAT3 · rs10765567

What the study found

Who was studied 6,141 European ancestry cases, 59,475 European ancestry controls; replicated in 9,171 European ancestry cases, 406,168 European ancestry controls.

The effect Each copy of the A allele carried 1.14 times the odds of Retinal detachment or retinal break (95% confidence interval 1.11-1.18); p = 2 × 10−17.

How common The A allele had a frequency of about 63% in the people studied.

Where it sits Chromosome 11, band 11q14.3 — in an intron of FAT3.

What each result means

A/A Two copies of the version the research linked to Retinal detachment or retinal break. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/T One copy of the version the research linked to Retinal detachment or retinal break. That is a smaller link than two copies.
T/T No copy of the version the research linked to Retinal detachment or retinal break. This is the starting point the study compared everyone against.
Source

Questions about rs10765567

What is rs10765567?

rs10765567 is a single position in the genome, in or near the FAT3 gene. Published research associates it with retinal detachment or retinal break. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs10765567 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs10765567 come from?

GWAS Catalog, Human molecular genetics 2020, PMID:31816047. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Retinal detachment or retinal break (rs10765567). MyGeneLog™. https://www.mygenelog.com/variants/rs10765567

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