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Factor VII activity or levels

REEP3 · rs10761784

What the study found

Who was studied 24,075 European ancestry individuals, 3,420 African American individuals.

The effect Each copy of the A allele shifted the measure 0.011 higher; p = 4 × 10−9.

How common The A allele had a frequency of about 53% in the people studied.

Where it sits Chromosome 10, band 10q21.3 — in an intron of REEP3.

What each result means

A/A Two copies of the version the research linked to Factor VII activity or levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/T One copy of the version the research linked to Factor VII activity or levels. That is a smaller link than two copies.
T/T No copy of the version the research linked to Factor VII activity or levels. This is the starting point the study compared everyone against.
Source

Questions about rs10761784

What is rs10761784?

rs10761784 is a single position in the genome, in or near the REEP3 gene. Published research associates it with factor vii activity or levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs10761784 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs10761784 come from?

GWAS Catalog, Blood 2019, PMID:30642921. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Factor VII activity or levels (rs10761784). MyGeneLog™. https://www.mygenelog.com/variants/rs10761784

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