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Bone marrow fat fraction of right proximal femur

JMJD1C · rs10761756

What the study found

Who was studied 38,560 European ancestry individuals.

The effect Each copy of the T allele shifted the measure 0.0428 higher (95% confidence interval 0.029-0.057); p = 1 × 10−9.

Where it sits Chromosome 10, band 10q21.3 — in an intron of JMJD1C.

What each result means

C/C Published research associates this genotype with typical/baseline likelihood of Bone marrow fat fraction of right proximal femur — no copies of the reported risk allele.
C/T Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Bone marrow fat fraction of right proximal femur.
T/T Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Bone marrow fat fraction of right proximal femur compared to the general population.
Source

Questions about rs10761756

What is rs10761756?

rs10761756 is a single position in the genome, in or near the JMJD1C gene. Published research associates it with bone marrow fat fraction of right proximal femur. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs10761756 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs10761756 come from?

GWAS Catalog, Nature communications 2025, PMID:40796918. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Bone marrow fat fraction of right proximal femur (rs10761756). MyGeneLog™. https://www.mygenelog.com/variants/rs10761756

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