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Childhood asthma with severe exacerbations

ERMP1 · rs10758710

Where this position leads

Condition: Asthma

rs10758710 Condition: Asthma Asthma Condition rs10758710 rs10758710 ERMP1

What the study found

Who was studied 2,866 European ancestry cases, 65,415 European ancestry controls.

The effect Each copy of the T allele shifted the measure 0.17 higher (95% confidence interval 0.11-0.23); p = 3 × 10−9.

Where it sits Chromosome 9, band 9p24.1 — in an intron of ERMP1.

What each result means

C/C No copy of the version the research linked to Childhood asthma with severe exacerbations. This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to Childhood asthma with severe exacerbations. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Childhood asthma with severe exacerbations. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs10758710

What is rs10758710?

rs10758710 is a single position in the genome, in or near the ERMP1 gene. Published research associates it with childhood asthma with severe exacerbations. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs10758710 linked to?

On MyGeneLog this position is linked to Asthma. The research behind each link, and its sources, are set out on that condition page.

Does having rs10758710 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs10758710 come from?

GWAS Catalog, Nature communications 2020, PMID:33328473. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Childhood asthma with severe exacerbations (rs10758710). MyGeneLog™. https://www.mygenelog.com/variants/rs10758710

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