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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 315,284 European ancestry male individuals.
The effect
Each copy of the A allele shifted the measure 0.0161 higher (95% confidence interval 0.011-0.021); p = 2 × 10−9.
How common The A allele had a frequency of about 84% in the people studied.
Where it sits Chromosome 1, band 1p36.12 — between genes, 24 kb from PPIAP34.
What each result means
A/ATwo copies of the version the research linked to Waist-to-hip ratio adjusted for BMI. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/GOne copy of the version the research linked to Waist-to-hip ratio adjusted for BMI. That is a smaller link than two copies.
G/GNo copy of the version the research linked to Waist-to-hip ratio adjusted for BMI. This is the starting point the study compared everyone against.
Human molecular genetics · 2019 · PMID 30239722 · open access
Questions about rs10753534
What is rs10753534?
rs10753534 is a single position in the genome, in or near the near PPIAP34 gene. Published research associates it with waist-to-hip ratio adjusted for bmi. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs10753534 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs10753534 come from?
GWAS Catalog, Human molecular genetics 2019, PMID:30239722. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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Quoting this page
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Waist-to-hip ratio adjusted for BMI (rs10753534). MyGeneLog™. https://www.mygenelog.com/variants/rs10753534