Sensitive

Breast cancer

UBA52P7 · rs10744856

Where this position leads

Condition: Breast Cancer

rs10744856 Condition: Breast Cancer Breast Cancer Condition rs10744856 rs10744856 UBA52P7

What the study found

Who was studied 6,669 Japanese ancestry cases, 21,930 Japanese ancestry controls; replicated in 981 Japanese ancestry cases, 1,394 Japanese ancestry controls.

The effect Each copy of the G allele carried 1.13 times the odds of Breast cancer (95% confidence interval 1.083-1.178); p = 1 × 10−8.

How common The G allele had a frequency of about 63% in the people studied.

Where it sits Chromosome 12, band 12q24.21 — between genes, 195 kb from UBA52P7.

What each result means

A/A No copy of the version the research linked to Breast cancer. This is the starting point the study compared everyone against.
A/G One copy of the version the research linked to Breast cancer. That is a smaller link than two copies.
G/G Two copies of the version the research linked to Breast cancer. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs10744856

What is rs10744856?

rs10744856 is a single position in the genome, in or near the UBA52P7 gene. Published research associates it with breast cancer. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs10744856 linked to?

On MyGeneLog this position is linked to Breast Cancer. The research behind each link, and its sources, are set out on that condition page.

Does having rs10744856 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs10744856 come from?

GWAS Catalog, Scientific reports 2019, PMID:31757997. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Breast cancer (rs10744856). MyGeneLog™. https://www.mygenelog.com/variants/rs10744856

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