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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 34,532 European ancestry individuals, 5,156 individuals.
The effect
Each copy of the G allele shifted the measure 0.057 higher; p = 6 × 10−25.
How common The G allele had a frequency of about 41% in the people studied.
Where it sits Chromosome 10, band 10p11.23 — between genes, 134 kb from JCAD.
What each result means
A/ANo copy of the version the research linked to Descending thoracic aortic diameter. This is the starting point the study compared everyone against.
A/GOne copy of the version the research linked to Descending thoracic aortic diameter. That is a smaller link than two copies.
G/GTwo copies of the version the research linked to Descending thoracic aortic diameter. That is the strongest link of the three results. A link in a study is not a diagnosis.
Nature genetics · 2022 · PMID 34837083 · open access
Questions about rs10740811
What is rs10740811?
rs10740811 is a single position in the genome, in or near the near JCAD gene. Published research associates it with descending thoracic aortic diameter. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs10740811 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs10740811 come from?
GWAS Catalog, Nature genetics 2022, PMID:34837083. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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