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Monocyte percentage of white cells

SH2D3C · rs10739695

Where this position leads

Condition: Blood Cell Counts

rs10739695 Condition: Blood Cell Counts Blood Cell Counts Condition rs10739695 rs10739695 SH2D3C

What the study found

Who was studied 170,494 European ancestry individuals.

The effect Each copy of the G allele shifted the measure 0.0234 lower (95% confidence interval 0.016-0.03); p = 8 × 10−11.

How common The G allele had a frequency of about 57% in the people studied.

Where it sits Chromosome 9, band 9q34.11 — in an intron of SH2D3C.

What each result means

A/A Published research associates this genotype with typical/baseline likelihood of Monocyte percentage of white cells — no copies of the reported risk allele.
A/G Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Monocyte percentage of white cells.
G/G Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Monocyte percentage of white cells compared to the general population.
Source

Questions about rs10739695

What is rs10739695?

rs10739695 is a single position in the genome, in or near the SH2D3C gene. Published research associates it with monocyte percentage of white cells. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs10739695 linked to?

On MyGeneLog this position is linked to Blood Cell Counts. The research behind each link, and its sources, are set out on that condition page.

Does having rs10739695 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs10739695 come from?

GWAS Catalog, Cell 2016, PMID:27863252. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Monocyte percentage of white cells (rs10739695). MyGeneLog™. https://www.mygenelog.com/variants/rs10739695

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