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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 50,412 European ancestry individuals.
The effect
Each copy of the G allele shifted the measure 0.28 higher (95% confidence interval 0.26-0.3).
Where it sits Chromosome 1, band 1q31.3 — between genes, 14.5 kb from CFHR1.
What each result means
G/GTwo copies of the version the research linked to CFHR5 plasma levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
G/TOne copy of the version the research linked to CFHR5 plasma levels. That is a smaller link than two copies.
T/TNo copy of the version the research linked to CFHR5 plasma levels. This is the starting point the study compared everyone against.
Nature communications · 2023 · PMID 37286573 · open access
Questions about rs10737681
What is rs10737681?
rs10737681 is a single position in the genome, in or near the near CFHR1 gene. Published research associates it with cfhr5 plasma levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs10737681 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs10737681 come from?
GWAS Catalog, Nature communications 2023, PMID:37286573. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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