Standard

Sitting height ratio

C10orf90 · rs10736877

Where this position leads

Condition: Height

rs10736877 Condition: Height Height Condition rs10736877 rs10736877 C10orf90

What the study found

Who was studied 3,545 African American individuals, 12,965 European ancestry women, 8,625 European ancestry men.

The effect Each copy of the A allele shifted the measure 0.131 lower (95% confidence interval 0.086-0.176); p = 2 × 10−8.

How common The A allele had a frequency of about 51% in the people studied.

Where it sits Chromosome 10, band 10q26.2 — inside C10orf90.

What each result means

A/A Two copies of the version the research linked to Sitting height ratio. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to Sitting height ratio. That is a smaller link than two copies.
G/G No copy of the version the research linked to Sitting height ratio. This is the starting point the study compared everyone against.
Source

Questions about rs10736877

What is rs10736877?

rs10736877 is a single position in the genome, in or near the C10orf90 gene. Published research associates it with sitting height ratio. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs10736877 linked to?

On MyGeneLog this position is linked to Height. The research behind each link, and its sources, are set out on that condition page.

Does having rs10736877 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs10736877 come from?

GWAS Catalog, American journal of human genetics 2015, PMID:25865494. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Sitting height ratio (rs10736877). MyGeneLog™. https://www.mygenelog.com/variants/rs10736877

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